Ipamorelin is a synthetic pentapeptide (Aib-His-D-2-Nal-D-Phe-Lys-NH2) that acts as a selective agonist of the growth hormone secretagogue receptor (GHS-R1a), the receptor later identified as the ghrelin receptor. Contexx Research supplies Ipamorelin in Canada as a 10 mg lyophilized research peptide for receptor pharmacology and endocrine research.
Ipamorelin specifications
| Compound | Ipamorelin (NNC 26-0161) |
|---|---|
| Vial size | 10 mg |
| Form | Lyophilized powder |
| Purity | See lot COA |
| Sequence | Aib-His-D-2-Nal-D-Phe-Lys-NH2 |
| CAS number | 170851-70-4 |
| Molecular formula | C38H49N9O5 |
| Molecular weight | 711.9 g/mol |
| Storage (unopened) | −20 °C, dry, protected from light |
Research overview
Ipamorelin was described in 1998 by researchers at Novo Nordisk as the first selective growth hormone secretagogue. In rat pituitary cell and in-vivo rat experiments it released growth hormone with potency similar to GHRP-6, and unlike earlier secretagogues it did not raise ACTH or cortisol at comparable levels. That selectivity is the main reason it became a standard reference ligand [1].
Follow-up rat studies looked at longitudinal bone growth after repeated exposure [2] and at how somatotroph cells responded in vitro after chronic exposure in young female rats [3]. Together these papers give a useful picture of GHS-R1a pharmacology in rodent systems.
Researchers use Ipamorelin as a selective GHS-R1a tool compound in receptor binding, calcium signalling and pituitary cell secretion assays, and as a comparator in structure–activity studies of peptidyl and non-peptidyl secretagogues.
Selected references
- Raun K et al. Eur J Endocrinol. 1998. PubMed 9849822
- Johansen PB et al. Growth Horm IGF Res. 1999. PubMed 10373343
- Jiménez-Reina L et al. Histol Histopathol. 2002. PubMed 12168778
Storage and handling
Ipamorelin ships as a lyophilized (freeze-dried) powder. Dry material is far more stable than material in solution, so keep it in its dry, sealed state until you need it.
- Store unopened vials of Ipamorelin at −20 °C, dry and protected from light. Let the vial reach room temperature before opening to limit condensation.
- Prepare stock solutions in a solvent suited to your assay, label them with concentration and date, and keep them at 2–8 °C for short-term use.
- For longer storage of solutions, divide them into single-use aliquots and freeze them; avoid repeated freeze–thaw cycles.
- Handle with gloves and eye protection, following your laboratory’s standard chemical-hygiene practice.
See our guide to storing lyophilized peptides in the lab for more detail.
Quality and testing
Contexx Research independently tests every batch it releases. A lot-specific COA for Ipamorelin isn’t linked on this page yet. For questions about testing, contact info@contexxresearch.ca.
We don’t list purity figures in this description; the lot COA is the reference for identity and purity. Researchers should confirm identity and concentration with their own analytical methods where their protocol requires it.
Frequently asked questions
What’s included when I order Ipamorelin 10 mg?
One sealed vial containing 10 mg of Ipamorelin as a lyophilized powder. Reconstitution solution is sold separately.
Does Ipamorelin come with a Certificate of Analysis (COA)?
Every batch Contexx Research releases is independently tested. A lot-specific COA isn’t linked on this page yet; for testing questions, contact info@contexxresearch.ca.
How fast is shipping in Canada?
Orders are processed Monday to Friday, and most orders ship within 24 hours from Mississauga, Ontario, in secure, tamper-evident packaging. Orders placed on Friday afternoon (after the 12:00 PM ET cut-off) ship on Monday, when Canada Post resumes pickup, or on the next business day if Monday is a statutory holiday. Once your order ships, delivery typically takes 1–3 business days in Ontario and Quebec and 2–6 business days in the rest of Canada, and a tracking number is emailed to you. Orders over $250 CAD shipped within Canada qualify for free standard shipping. See our Shipping Policy for details.
How should Ipamorelin be stored?
Store unopened vials at −20 °C, dry and protected from light. After reconstitution, keep solutions at 2–8 °C for short-term use, or freeze single-use aliquots and avoid repeated freeze–thaw cycles.
What does “research use only” mean?
“Research use only” means Ipamorelin is sold only as a reference material for in-vitro laboratory and analytical research by qualified professionals. It is not for use in humans or animals, not for diagnostic use, and not a drug, natural health product, food, supplement or cosmetic.
Research use only
Ipamorelin is sold by Contexx Research Inc. strictly as a reference material for in-vitro laboratory research and analytical use by qualified professionals. It is not a drug, natural health product, food, dietary supplement or cosmetic. It is not intended for use in humans or animals, for diagnostic purposes, or for ingestion or any other form of administration to a living organism. Nothing on this page describes or implies any effect in humans or animals. Purchasers are responsible for handling, storage and disposal in line with applicable laws and their institution’s policies. By ordering, you confirm that you are purchasing for legitimate laboratory research and agree to our Terms and Conditions.

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